Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hsd3b  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase cluster
Results	Reference
1	J:308912 Bergeron F, Boulende Sab A, Bouchard MF, Taniguchi H, Souchkova O, Brousseau C, Tremblay JJ, Pilon N, Viger RS, Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse. Andrology. 2019 May;7(3):357-372
1	J:292639 Cen C, Chen M, Zhou J, Zhang L, Duo S, Jiang L, Hou X, Gao F, Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development. Biol Reprod. 2020 Jun 23;103(1):60-69
1	J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85
1	J:258502 Fouchecourt S, Livera G, Messiaen S, Fumel B, Parent AS, Marine JC, Monget P, Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility. Cell Death Differ. 2016 Mar;23(3):521-30
1	J:313927 Gannon AL, O'Hara L, Mason IJ, Jorgensen A, Frederiksen H, Curley M, Milne L, Smith S, Mitchell RT, Smith LB, Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity. Front Endocrinol (Lausanne). 2020;11:599869
1*	J:111787 Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Lecureuil C, Guillou F, Huff V, The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11987-92
1	J:189572 Huang CC, Liu C, Yao HH, Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice. Mol Cell Endocrinol. 2012 Sep 25;361(1-2):165-71
1*	J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66
1	J:227517 Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, Hidema S, Oe T, Goto T, Clevers H, Nawa A, Nishimori K, Lgr4 controls specialization of female gonads in mice. Biol Reprod. 2015 Oct;93(4):90
1	J:313942 Kuroki S, Maeda R, Yano M, Kitano S, Miyachi H, Fukuda M, Shinkai Y, Tachibana M, H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline. Stem Cell Reports. 2020 Aug 11;15(2):424-438
1	J:154048 Li H, MacLean G, Cameron D, Clagett-Dame M, Petkovich M, Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. PLoS One. 2009;4(10):e7501
1	J:222787 Liu C, Peng J, Matzuk MM, Yao HH, Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells. Nat Commun. 2015;6:6934
1	J:322043 Liu M, Deng W, Tang L, Liu M, Bao H, Guo C, Zhang C, Lu J, Wang H, Lu Z, Kong S, Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling. Nat Commun. 2022 Feb 22;13(1):1006
1	J:307535 Liu X, Schneble-Lohnert N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jorss T, Ori A, Godmann M, Wang ZQ, The N-terminal BRCT domain determines MCPH1 function in brain development and fertility. Cell Death Dis. 2021 Feb 1;12(2):143
1	J:326550 Mayere C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kuhne F, Gantar I, Tang F, Stevant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S, Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad. Sci Adv. 2022 May 27;8(21):eabm0972
1	J:346442 Migale R, Neumann M, Mitter R, Rafiee MR, Wood S, Olsen J, Lovell-Badge R, FOXL2 interaction with different binding partners regulates the dynamics of ovarian development. Sci Adv. 2024 Mar 22;10(12):eadl0788
1	J:300503 Nicol B, Rodriguez K, Yao HH, Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice. Biol Reprod. 2020 Oct 29;103(5):966-977
1*	J:212212 O'Hara L, York JP, Zhang P, Smith LB, Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice. PLoS One. 2014;9(1):e84541
1	J:98517 Park SY, Meeks JJ, Raverot G, Pfaff LE, Weiss J, Hammer GD, Jameson JL, Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development. Development. 2005 May;132(10):2415-23
1	J:290205 Richardson N, Gillot I, Gregoire EP, Youssef SA, de Rooij D, de Bruin A, De Cian MC, Chaboissier MC, Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals. Elife. 2020 May 26;9:e53972
1*	J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546
1	J:164361 Tanwar PS, Zhang L, Tanaka Y, Taketo MM, Donahoe PK, Teixeira JM, Focal Mullerian duct retention in male mice with constitutively activated beta-catenin expression in the Mullerian duct mesenchyme. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16142-7
1	J:258557 Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S, Wu X, Wang H, Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice. Cell Death Differ. 2016 Jan;23(1):169-81
1	J:217603 Vanhoutteghem A, Messiaen S, Herve F, Delhomme B, Moison D, Petit JM, Rouiller-Fabre V, Livera G, Djian P, The zinc-finger protein basonuclin 2 is required for proper mitotic arrest, prevention of premature meiotic initiation and meiotic progression in mouse male germ cells. Development. 2014 Nov;141(22):4298-310
1	J:220734 Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F, Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4003-8
1	J:310317 Zhang S, Kong S, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lu J, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang H, Wang YL, Li B, Chen Q, Duan E, Wang H, Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms. Cell Res. 2014 Aug;24(8):925-42
1*	J:220472 Zhao L, Svingen T, Ng ET, Koopman P, Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8